PD-1 anticorps

N° du produit ABIN4949386

L’anticorps Lapin Polyclonal anti-PD-1 a été validé pour FACS, IF et IHC (p). Il convient pour détecter PD-1 dans des échantillons de Humain.

Aperçu rapide pour PD-1 anticorps (ABIN4949386)

Antigène: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PD-1 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-PD-1 anticorps

Purification: Protein A affinity chromatography

Immunogène: A full-length human protein was used as the immunogen for the PD1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Titering of the PD1 antibody may be required for optimal performance.\. Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT,Immunofluorescence: 1-2 μg/mL,FACS: 0.5-1 μg/10e6 cells in 0.1ml

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the PD1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur PD-1

Antigène: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Autre désignation: PDCD1 / PD-1

Sujet: PDCD1 (Programmed cell death-1 protein), also called PD1 and CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD1 is expressed by few B-cells, so may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma.

Pathways: Cancer Immune Checkpoints